A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies
Author:
Funder
Cancer Research UK
Wellcome Trust
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology
Link
http://www.nature.com/articles/s43018-020-0027-5.pdf
Reference34 articles.
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3. Van Hoeck, A., Tjoonk, N. H., van Boxtel, R. & Cuppen, E. Portrait of a cancer: mutational signature analyses for cancer diagnostics. BMC Cancer 19, 457 (2019).
4. Alexandrov, L. B., Nik-Zainal, S., Wedge, D. C., Campbell, P. J. & Stratton, M. R. Deciphering signatures of mutational processes operative in human cancer. Cell Rep. 3, 246–259 (2013).
5. Baez-Ortega, A. & Gori, K. Computational approaches for discovery of mutational signatures in cancer. Brief Bioinform. 20, 77–88 (2019).
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