Concurrent delivery of immune checkpoint blockade modulates T cell dynamics to enhance neoantigen vaccine-generated antitumor immunity
Author:
Funder
Cancer Prevention and Research Institute of Texas
U.S. Department of Health & Human Services | NIH | National Cancer Institute
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology
Link
https://www.nature.com/articles/s43018-022-00352-7.pdf
Reference58 articles.
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3. Waldman, A. D., Fritz, J. M. & Lenardo, M. J. A guide to cancer immunotherapy: from T cell basic science to clinical practice. Nat. Rev. Immunol. 20, 651–668 (2020).
4. Reinherz, E. L. αβ TCR-mediated recognition: relevance to tumor-antigen discovery and cancer immunotherapy. Cancer Immunol. Res. 3, 305–312 (2015).
5. Zamora, A. E., Crawford, J. C. & Thomas, P. G. Hitting the target: how T cells detect and eliminate tumors. J. Immunol. 200, 392–399 (2018).
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