Targeted disruption of the EZH2–EED complex inhibits EZH2-dependent cancer-Reference-Cited by-同舟云学术

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Targeted disruption of the EZH2–EED complex inhibits EZH2-dependent cancer

Published:2013-08-25 Issue:10 Volume:9 Page:643-650
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Kim Woojin,Bird Gregory H,Neff Tobias,Guo Guoji,Kerenyi Marc A,Walensky Loren D,Orkin Stuart H

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.1331.pdf

Reference54 articles.

1. Cao, R. Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 298, 1039–1043 (2002).

2. Czermin, B. et al. Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell 111, 185–196 (2002).

3. Müller, J. et al. Histone methyltransferase activity of a Drosophila Polycomb group repressor complex. Cell 111, 197–208 (2002).

4. Kuzmichev, A. Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein. Genes Dev. 16, 2893–2905 (2002).

5. Varambally, S. et al. The Polycomb group protein EZH2 is involved in progression of prostate cancer. Nature 419, 624–629 (2002).

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