Precise small-molecule recognition of a toxic CUG RNA repeat expansion-Reference-Cited by-同舟云学术

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Precise small-molecule recognition of a toxic CUG RNA repeat expansion

Published:2016-12-12 Issue:2 Volume:13 Page:188-193
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Rzuczek Suzanne G,Colgan Lesley A,Nakai Yoshio,Cameron Michael D,Furling Denis,Yasuda Ryohei,Disney Matthew D^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.2251.pdf

Reference39 articles.

1. Schlünzen, F. et al. Structural basis for the interaction of antibiotics with the peptidyl transferase center in eubacteria. Nature 413, 814–821 (2001).

2. Carter, A.P. et al. Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics. Nature 407, 340–348 (2000).

3. Blount, K.F. et al. Novel riboswitch-binding flavin analog that protects mice against Clostridium difficile infection without inhibiting cecal flora. Antimicrob. Agents Chemother. 59, 5736–5746 (2015).

4. Howe, J.A. et al. Selective small-molecule inhibition of an RNA structural element. Nature 526, 672–677 (2015).

5. Brook, J.D. et al. Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the 3′ end of a transcript encoding a protein kinase family member. Cell 68, 799–808 (1992).

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