Allosteric inhibition through suppression of transient conformational states
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nchembio.1250.pdf
Reference45 articles.
1. Wells, J.A. & McClendon, C.L. Reaching for high-hanging fruit in drug discovery at protein-protein interfaces. Nature 450, 1001–1009 (2007).
2. Lee, G.M. & Craik, C.S. Trapping moving targets with small molecules. Science 324, 213–215 (2009).
3. Hardy, J.A. & Wells, J.A. Searching for new allosteric sites in enzymes. Curr. Opin. Struct. Biol. 14, 706–715 (2004).
4. Groebe, D.R. In search of negative allosteric modulators of biological targets. Drug Discov. Today 14, 41–49 (2009).
5. Maksay, G. Allostery in pharmacology: thermodynamics, evolution and design. Prog. Biophys. Mol. Biol. 106, 463–473 (2011).
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