Tunable and reversible drug control of protein production via a self-excising degron-Reference-Cited by-同舟云学术

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Tunable and reversible drug control of protein production via a self-excising degron

Published:2015-07-27 Issue:9 Volume:11 Page:713-720
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Chung Hokyung K,Jacobs Conor L,Huo Yunwen,Yang Jin,Krumm Stefanie A,Plemper Richard K,Tsien Roger Y,Lin Michael Z

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.1869.pdf

Reference56 articles.

1. Sigoillot, F.D. & King, R.W. Vigilance and validation: keys to success in RNAi screening. ACS Chem. Biol. 6, 47–60 (2011).

2. Vogel, C. & Marcotte, E.M. Insights into the regulation of protein abundance from proteomic and transcriptomic analyses. Nat. Rev. Genet. 13, 227–232 (2012).

3. Wu, L. et al. Variation and genetic control of protein abundance in humans. Nature 499, 79–82 (2013).

4. Battle, A. et al. Genomic variation. Impact of regulatory variation from RNA to protein. Science 347, 664–667 (2015).

5. Huang, C.J. et al. Conditional expression of a myocardium-specific transgene in zebrafish transgenic lines. Dev. Dyn. 233, 1294–1303 (2005).

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