Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation-Reference-Cited by-同舟云学术

Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation

Published:2006-07-23 Issue:9 Volume:2 Page:474-479
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Strom Evguenia,Sathe Swati,Komarov Pavel G,Chernova Olga B,Pavlovska Ivanda,Shyshynova Inna,Bosykh Dmitry A,Burdelya Lyudmila G,Macklis Roger M,Skaliter Rami,Komarova Elena A,Gudkov Andrei V

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio809.pdf

Reference30 articles.

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2. Komarov, P.G. et al. A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Science 285, 1733–1737 (1999).

3. Botchkarev, V.A. et al. p53 is essential for chemotherapy-induced hair loss. Cancer Res. 60, 5002–5006 (2000).

4. Komarova, E.A. & Gudkov, A.V. Chemoprotection from p53-dependent apoptosis: potential clinical applications of the p53 inhibitors. Biochem. Pharmacol. 62, 657–667 (2001).

5. Gudkov, A.V. & Komarova, E.A. The role of p53 in determining sensitivity to radiotherapy. Nat. Rev. Cancer 3, 117–129 (2003).

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