Phenylalanine assembly into toxic fibrils suggests amyloid etiology in phenylketonuria-Reference-Cited by-同舟云学术

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Phenylalanine assembly into toxic fibrils suggests amyloid etiology in phenylketonuria

Published:2012-06-17 Issue:8 Volume:8 Page:701-706
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Adler-Abramovich Lihi,Vaks Lilach,Carny Ohad,Trudler Dorit,Magno Andrea,Caflisch Amedeo,Frenkel Dan,Gazit Ehud

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.1002.pdf

Reference28 articles.

1. Hanley, W.B. Adult phenylketonuria. Am. J. Med. 117, 590–595 (2004).

2. Surtees, R. & Blau, N. The neurochemistry of phenylketonuria. Eur. J. Pediatr. 159 (suppl.), S109–S113 (2000).

3. Choi, T.B. & Pardridge, W.M. Phenylalanine transport at the human blood-brain barrier. Studies with isolated human brain capillaries. J. Biol. Chem. 261, 6536–6541 (1986).

4. Krause, W. et al. Biochemical and neuropsychological effects of elevated plasma phenylalanine in patients with treated phenylketonuria. A model for the study of phenylalanine and brain function in man. J. Clin. Invest. 75, 40–48 (1985).

5. MacDonald, A., Gokmen-Ozel, H., van Rijn, M. & Burgard, P. The reality of dietary compliance in the management of phenylketonuria. J. Inherit. Metab. Dis. 33, 665–670 (2010).

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