A diversity-oriented synthesis approach to macrocycles via oxidative ring expansion
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nchembio.911.pdf
Reference50 articles.
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2. Wessjohann, L.A., Ruijter, E., Garcia-Rivera, D. & Brandt, W. What can a chemist learn from nature's macrocycles?–A brief, conceptual view. Mol. Divers. 9, 171–186 (2005).
3. Sánchez-Pedregal, V.M. et al. The tubulin-bound conformation of discodermolide derived by NMR studies in solution supports a common pharmacophore model for epothilone and discodermolide. Angew. Chem. Int. Ed. Engl. 45, 7388–7394 (2006).
4. Canales, A. et al. The bound conformation of microtubule-stabilizing agents: NMR insights into the bioactive 3D structure of discodermolide and dictyostatin. Chem. Eur. J. 14, 7557–7569 (2008).
5. Knust, H. & Hoffmann, R.W. Synthesis and conformational analysis of macrocyclic dilactones mimicking the pharmacophore of aplysiatoxin. Helv. Chim. Acta 86, 1871–1893 (2003).
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