Identifying off-target effects and hidden phenotypes of drugs in human cells-Reference-Cited by-同舟云学术

Identifying off-target effects and hidden phenotypes of drugs in human cells

Published:2006-05-07 Issue:6 Volume:2 Page:329-337
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

MacDonald Marnie L,Lamerdin Jane,Owens Stephen,Keon Brigitte H,Bilter Graham K,Shang Zhidi,Huang Zhengping,Yu Helen,Dias Jennifer,Minami Tomoe,Michnick Stephen W,Westwick John K

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio790.pdf

Reference47 articles.

1. Stoughton, R.B. & Friend, S.H. How molecular profiling could revolutionize drug discovery. Nat. Rev. Drug Discov. 4, 345–350 (2005).

2. Tian, Q. et al. Integrated genomic and proteomic analyses of gene expression in Mammalian cells. Mol. Cell. Proteomics 3, 960–969 (2004).

3. Miklos, G.L. & Maleszka, R. Microarray reality checks in the context of a complex disease. Nat. Biotechnol. 22, 615–621 (2004).

4. Ghosh, I., Hamilton, A.D. & Regan, L. Antiparallel leucine zipper-directed protein reassembly: application to the green fluorescent protein. J. Am. Chem. Soc. 122, 5658–5659 (2000).

5. Michnick, S.W., Remy, I., Campbell-Valois, F.X., Vallee-Belisle, A. & Pelletier, J.N. Detection of protein-protein interactions by protein fragment complementation strategies. Methods Enzymol. 328, 208–230 (2000).

Cited by 281 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Transient infection of Euprymna scolopes with an engineered D-alanine auxotroph of Vibrio fischeri;Applied and Environmental Microbiology;2024-09-05

2. Exploiting protein domain modularity to enable synthetic control of engineered cells;Current Opinion in Biomedical Engineering;2024-09

3. Structural analysis of genomic and proteomic signatures reveal dynamic expression of intrinsically disordered regions in breast cancer;iScience;2024-09

4. HIV-1 Gag Compact form Stabilized by Intramolecular Interactions is Crucial for Infectious Particle Production;Journal of Molecular Biology;2024-08

5. Green and sustainable hydrogels based on quaternized chitosan to enhance wound healing;Chemical Engineering Journal;2024-07