Small-molecule inhibition of APT1 affects Ras localization and signaling-Reference-Cited by-同舟云学术

Small-molecule inhibition of APT1 affects Ras localization and signaling

Published:2010-04-25 Issue:6 Volume:6 Page:449-456
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Dekker Frank J,Rocks Oliver,Vartak Nachiket,Menninger Sascha,Hedberg Christian,Balamurugan Rengarajan,Wetzel Stefan,Renner Steffen,Gerauer Marc,Schölermann Beate,Rusch Marion,Kramer John W,Rauh Daniel,Coates Geoffrey W,Brunsveld Luc,Bastiaens Philippe I H,Waldmann Herbert

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.362.pdf

Reference40 articles.

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2. Jennings, B.C. et al. 2-Bromopalmitate and 2-(2-hydroxy-5-nitro- benzylidene)-benzo[b]thiophen-3-one inhibit DHHC-mediated palmitoylation in vitro. J. Lipid Res. 50, 233–242 (2009).

3. Greaves, J. & Chamberlain, L.H. Palmitoylation-dependent protein sorting. J. Cell Biol. 176, 249–254 (2007).

4. Rocks, O. et al. An acylation cycle regulates localization and activity of palmitoylated Ras isoforms. Science 307, 1746–1752 (2005).

5. Rocks, O. et al. The palmitoylation machinery is a generic sorting system for peripheral membrane proteins. Cell Published online 30 April 2010; doi:10.1016/j.cell.2010.04.007.

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