A small-molecule inhibitor shows that pirin regulates migration of melanoma cells
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nchembio.423.pdf
Reference50 articles.
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3. Orzaez, D., de Jong, A. & Woltering, E.J. A tomato homologue of the human protein PIRIN is induced during programmed cell death. Plant Mol. Biol. 46, 459–468 (2001).
4. Lapik, Y.R. & Kaufman, L.S. The Arabidopsis cupin domain protein AtPirin1 interacts with the G protein alpha-subunit GPA1 and regulates seed germination and early seedling development. Plant Cell 15, 1578–1590 (2003).
5. Adams, M. & Jia, Z. Structural and biochemical analysis reveal pirins to possess quercetinase activity. J. Biol. Chem. 280, 28675–28682 (2005).
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