Structural and conformational determinants of macrocycle cell permeability-Reference-Cited by-同舟云学术

Structural and conformational determinants of macrocycle cell permeability

Published:2016-10-17 Issue:12 Volume:12 Page:1065-1074
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Over Björn^ORCID,Matsson Pär^ORCID,Tyrchan Christian,Artursson Per,Doak Bradley C,Foley Michael A,Hilgendorf Constanze,Johnston Stephen E,Lee Maurice D,Lewis Richard J,McCarren Patrick,Muncipinto Giovanni,Norinder Ulf,Perry Matthew W D,Duvall Jeremy R,Kihlberg Jan

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.2203.pdf

Reference52 articles.

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3. Doak, B.C., Over, B., Giordanetto, F. & Kihlberg, J. Oral druggable space beyond the rule of 5: insights from drugs and clinical candidates. Chem. Biol. 21, 1115–1142 (2014).

4. Driggers, E.M., Hale, S.P., Lee, J. & Terrett, N.K. The exploration of macrocycles for drug discovery--an underexploited structural class. Nat. Rev. Drug Discov. 7, 608–624 (2008).

5. Surade, S. & Blundell, T.L. Structural biology and drug discovery of difficult targets: the limits of ligandability. Chem. Biol. 19, 42–50 (2012).

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