Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death-Reference-Cited by-同舟云学术

Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death

Published:2013-07-28 Issue:9 Volume:9 Page:548-556
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Magnaghi Paola,D'Alessio Roberto,Valsasina Barbara,Avanzi Nilla,Rizzi Simona,Asa Daniela,Gasparri Fabio,Cozzi Liviana,Cucchi Ulisse,Orrenius Christian,Polucci Paolo,Ballinari Dario,Perrera Claudia,Leone Antonella,Cervi Giovanni,Casale Elena,Xiao Yang,Wong Chihunt,Anderson Daniel J,Galvani Arturo,Donati Daniele,O'Brien Tom,Jackson Peter K,Isacchi Antonella

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.1313.pdf

Reference48 articles.

1. Ogura, T. & Wilkinson, A.J. AAA+ superfamily ATPases: common structure—diverse function. Genes Cells 6, 575–597 (2001).

2. DeLaBarre, B. & Brunger, A.T. Nucleotide dependent motion and mechanism of action of p97/VCP. J. Mol. Biol. 347, 437–452 (2005).

3. Beuron, F. et al. Conformational changes in the AAA ATPase p97–p47 adaptor complex. EMBO J. 25, 1967–1976 (2006).

4. Davies, J.M., Brunger, A.T. & Weis, W.I. Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change. Structure 16, 715–726 (2008).

5. Rouiller, I. et al. Conformational changes of the multifunction p97 AAA ATPase during its ATPase cycle. Nat. Struct. Biol. 9, 950–957 (2002).

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