Partial DNA-guided Cas9 enables genome editing with reduced off-target activity-Reference-Cited by-同舟云学术

Partial DNA-guided Cas9 enables genome editing with reduced off-target activity

Published:2018-01-29 Issue:3 Volume:14 Page:311-316
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Yin Hao,Song Chun-Qing,Suresh Sneha,Kwan Suet-Yan,Wu Qiongqiong,Walsh Stephen,Ding Junmei,Bogorad Roman L,Zhu Lihua Julie,Wolfe Scot A,Koteliansky Victor,Xue Wen^ORCID,Langer Robert,Anderson Daniel G

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.2559.pdf

Reference48 articles.

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2. Mali, P. et al. RNA-guided human genome engineering via Cas9. Science 339, 823–826 (2013).

3. Doudna, J.A. & Charpentier, E. Genome editing. The new frontier of genome engineering with CRISPR-Cas9. Science 346, 1258096 (2014).

4. Jinek, M. et al. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337, 816–821 (2012).

5. Cox, D.B., Platt, R.J. & Zhang, F. Therapeutic genome editing: prospects and challenges. Nat. Med. 21, 121–131 (2015).

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