(R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2-Reference-Cited by-同舟云学术

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(R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2

Published:2011-09-25 Issue:11 Volume:7 Page:803-809
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Duggan Kelsey C,Hermanson Daniel J,Musee Joel,Prusakiewicz Jeffery J,Scheib Jami L,Carter Bruce D,Banerjee Surajit,Oates J A,Marnett Lawrence J

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.663.pdf

Reference48 articles.

1. Di Marzo, V., De Petrocellis, L. & Bisogno, T. The biosynthesis, fate and pharmacological properties of endocannabinoids. Handb. Exp. Pharmacol. 168, 147–185 (2005).

2. Piomelli, D. The molecular logic of endocannabinoid signalling. Nat. Rev. Neurosci. 4, 873–884 (2003).

3. Kogan, N.M. & Mechoulam, R. The chemistry of endocannabinoids. J. Endocrinol. Invest. 29, 3–14 (2006).

4. Ueda, N. et al. Lipoxygenase-catalyzed oxygenation of arachidonylethanolamide, a cannabinoid receptor agonist. Biochim. Biophys. Acta 1254, 127–134 (1995).

5. Yu, M., Ives, D. & Ramesha, C.S. Synthesis of prostaglandin E2 ethanolamide from anandamide by cyclooxygenase-2. J. Biol. Chem. 272, 21181–21186 (1997).

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