Atomic mutagenesis reveals A2660 of 23S ribosomal RNA as key to EF-G GTPase activation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nchembio.341.pdf
Reference48 articles.
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2. Chirkova, A., Erlacher, M., Micura, R. & Polacek, N. Chemically engineered ribosomes: a new frontier in synthetic biology. Curr. Org. Chem. 14, 148–161 (2010).
3. Hauryliuk, V. et al. The pretranslocation ribosome is targeted by GTP-bound EF-G in partially activated form. Proc. Natl. Acad. Sci. USA 105, 15678–15683 (2008).
4. Rodnina, M.V., Savelsbergh, A., Katunin, V.I. & Wintermeyer, W. Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome. Nature 385, 37–41 (1997).
5. Zavialov, A.V., Hauryliuk, V.V. & Ehrenberg, M. Guanine-nucleotide exchange on ribosome-bound elongation factor G initiates the translocation of tRNAs. J. Biol. 4, 9 (2005).
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