Correlating chemical sensitivity and basal gene expression reveals mechanism of action-Reference-Cited by-同舟云学术

Correlating chemical sensitivity and basal gene expression reveals mechanism of action

Published:2015-12-14 Issue:2 Volume:12 Page:109-116
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Rees Matthew G,Seashore-Ludlow Brinton^ORCID,Cheah Jaime H,Adams Drew J,Price Edmund V,Gill Shubhroz,Javaid Sarah,Coletti Matthew E,Jones Victor L,Bodycombe Nicole E,Soule Christian K,Alexander Benjamin^ORCID,Li Ava,Montgomery Philip^ORCID,Kotz Joanne D,Hon C Suk-Yee,Munoz Benito,Liefeld Ted,Dančík Vlado,Haber Daniel A,Clish Clary B^ORCID,Bittker Joshua A^ORCID,Palmer Michelle,Wagner Bridget K,Clemons Paul A,Shamji Alykhan F,Schreiber Stuart L^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.1986.pdf

Reference49 articles.

1. Hughes, J.P., Rees, S., Kalindjian, S.B. & Philpott, K.L. Principles of early drug discovery. Br. J. Pharmacol. 162, 1239–1249 (2011).

2. Schenone, M., Dančík, V., Wagner, B.K. & Clemons, P.A. Target identification and mechanism of action in chemical biology and drug discovery. Nat. Chem. Biol. 9, 232–240 (2013).

3. Swinney, D.C. & Anthony, J. How were new medicines discovered? Nat. Rev. Drug Discov. 10, 507–519 (2011).

4. Subramanian, A. et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl. Acad. Sci. USA 102, 15545–15550 (2005).

5. Hughes, T.R. et al. Functional discovery via a compendium of expression profiles. Cell 102, 109–126 (2000).

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