Profiling drugs for rheumatoid arthritis that inhibit synovial fibroblast activation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nchembio.2211.pdf
Reference52 articles.
1. Scott, D.L., Wolfe, F. & Huizinga, T.W. Rheumatoid arthritis. Lancet 376, 1094–1108 (2010).
2. McInnes, I.B. & Schett, G. The pathogenesis of rheumatoid arthritis. N. Engl. J. Med. 365, 2205–2219 (2011).
3. Taylor, P.C. & Feldmann, M. Anti-TNF biologic agents: still the therapy of choice for rheumatoid arthritis. Nat. Rev. Rheumatol. 5, 578–582 (2009).
4. Emery, P. et al. IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial. Ann. Rheum. Dis. 67, 1516–1523 (2008).
5. Stanczyk, J., Ospelt, C. & Gay, S. Is there a future for small molecule drugs in the treatment of rheumatic diseases? Curr. Opin. Rheumatol. 20, 257–262 (2008).
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