Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate-Reference-Cited by-同舟云学术

Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate

Published:2017-08-07 Issue:10 Volume:13 Page:1081-1087
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Oslund Rob C,Su Xiaoyang,Haugbro Michael,Kee Jung-Min^ORCID,Esposito Mark,David Yael,Wang Boyuan,Ge Eva,Perlman David H,Kang Yibin,Muir Tom W,Rabinowitz Joshua D

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.2453.pdf

Reference43 articles.

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2. Hitosugi, T. et al. Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth. Cancer Cell 22, 585–600 (2012).

3. Possemato, R. et al. Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. Nature 476, 346–350 (2011).

4. Labuschagne, C.F., van den Broek, N.J., Mackay, G.M., Vousden, K.H. & Maddocks, O.D. Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells. Cell Rep. 7, 1248–1258 (2014).

5. Mattaini, K.R. et al. An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation. Cancer Metab. 3, 5 (2015).

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