Click-generated triazole ureas as ultrapotent in vivo–active serine hydrolase inhibitors-Reference-Cited by-同舟云学术

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Click-generated triazole ureas as ultrapotent in vivo–active serine hydrolase inhibitors

Published:2011-05-15 Issue:7 Volume:7 Page:469-478
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Adibekian Alexander,Martin Brent R,Wang Chu,Hsu Ku-Lung,Bachovchin Daniel A,Niessen Sherry,Hoover Heather,Cravatt Benjamin F

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/nchembio.579.pdf

Reference50 articles.

1. Simon, G.M. & Cravatt, B.F. Activity-based proteomics of enzyme superfamilies: serine hydrolases as a case study. J. Biol. Chem. 285, 11051–11055 (2010).

2. Henness, S. & Perry, C.M. Orlistat: a review of its use in the management of obesity. Drugs 66, 1625–1656 (2006).

3. Thornberry, N.A. & Weber, A.E. Discovery of JANUVIA (Sitagliptin), a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. Curr. Top. Med. Chem. 7, 557–568 (2007).

4. Kluge, A.F. & Petter, R.C. Acylating drugs: redesigning natural covalent inhibitors. Curr. Opin. Chem. Biol. 14, 421–427 (2010).

5. Racchi, M., Mazzucchelli, M., Porrello, E., Lanni, C. & Govoni, S. Acetylcholinesterase inhibitors: novel activities of old molecules. Pharmacol. Res. 50, 441–451 (2004).

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