Acquired EGFR C797S mutation mediates resistance to AZD9291 in non–small cell lung cancer harboring EGFR T790M-Reference-Cited by-同舟云学术

Acquired EGFR C797S mutation mediates resistance to AZD9291 in non–small cell lung cancer harboring EGFR T790M

Published:2015-05-04 Issue:6 Volume:21 Page:560-562
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Thress Kenneth S,Paweletz Cloud P,Felip Enriqueta,Cho Byoung Chul,Stetson Daniel,Dougherty Brian,Lai Zhongwu,Markovets Aleksandra,Vivancos Ana,Kuang Yanan,Ercan Dalia,Matthews Sarah E,Cantarini Mireille,Barrett J Carl,Jänne Pasi A,Oxnard Geoffrey R

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.3854.pdf

Reference16 articles.

1. Mok, T.S. et al. N. Engl. J. Med. 361, 947–957 (2009).

2. Rosell, R. et al. N. Engl. J. Med. 361, 958–967 (2009).

3. Arcila, M.E. et al. Clin. Cancer Res. 17, 1169–1180 (2011).

4. Sequist, L.V. et al. Sci. Transl. Med. 3, 75ra26 (2011).

5. Zhou, W. et al. Nature 462, 1070–1074 (2009).

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