Toll-like receptors as potential therapeutic targets for multiple diseases
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd914.pdf
Reference119 articles.
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3. Poltorak, A. et al. Defective LPS signalling in C3H/Hej and C57BL/10ScCr mice: mutations in TLR-4 gene. Science 282, 2085–2088 (1998).The first report to show that mammalian TLRs are involved in host defence.
4. Medzhitov, R. Toll-like receptors and innate immunity. Nature Immunol. 1, 135–145 (2001).
5. Imler, J. L. & Hoffmann, J. A. Toll-like receptors in innate immunity. Trends Cell Biol. 11, 304–311 (2001).
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