Inactivation of the E-Cadherin Gene in Sporadic Diffuse-Type Gastric Cancer

Author:

Ascaño Jennifer J,Frierson Henry,Moskaluk Christopher A,Harper Jeffrey C,Roviello Franco,Jackson Charles E,El-Rifai Wa'el,Vindigni Carla,Tosi Piero,Powell Steven M

Publisher

Springer Science and Business Media LLC

Subject

Pathology and Forensic Medicine

Reference35 articles.

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2. Mayer B, Johnson JP, Leitl F, Jauch KW, Heiss MM, Schildberg FW, et al. E-cadherin expression in primary and metastatic gastric cancer: down-regulation correlates with cellular dedifferentiation and glandular disintegration. Cancer Res 1993; 53: 1690–1695.

3. Handschuh G, Candidus S, Luber B, Reich U, Schott C, Oswald S, et al. Tumour-associated E-cadherin mutations alter cellular morphology, decrease cellular adhesion and increase cellular motility. Oncogene 1999; 18: 4301–4312.

4. Takeichi M . Cadherins in cancer: implications for invasion and metastasis. Curr Opin Cell Biol 1993; 5: 806–811.

5. Birchmeier W, Behrens J . Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness. Biochim Biophys Acta 1994; 1198: 11–26.

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