Differential expression of enhancer of zeste homolog 2 (EZH2) protein in small cell and aggressive B-cell non-Hodgkin lymphomas and differential regulation of EZH2 expression by p-ERK1/2 and MYC in aggressive B-cell lymphomas
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pathology and Forensic Medicine
Link
http://www.nature.com/articles/modpathol2016114.pdf
Reference43 articles.
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2. Fujii S, Ito K, Ito Y et al. Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation. J Biol Chem 2008;283:17324–17332.
3. Fujii S, Tokita K, Wada N et al. MEK–ERK pathway regulates EZH2 overexpression in association with aggressive breast cancer subtypes. Oncogene 2011;30:4118–4128.
4. Geng J, Li X, Zhou Z et al. EZH2 promotes tumor progression via regulating VEGF-A/AKT signaling in non-small cell lung cancer. Cancer Lett 2015;359:275–287.
5. Gonzalez M, DuPrie M, Krueger H et al. Histone methyltransferase EZH2 induces Akt-dependent genomic instability and BRCA1 inhibition in breast cancer. Cancer Res 2001;71:2360–2370.
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