Clinical validation of an array CGH test for HER2 status in breast cancer reveals that polysomy 17 is a rare event
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pathology and Forensic Medicine
Link
http://www.nature.com/articles/modpathol200978.pdf
Reference28 articles.
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3. Barrett C, Magee H, O'Toole D, et al. Amplification of the HER2 gene in breast cancers testing 2+ weak positive by HercepTest immunohistochemistry: false-positive or false-negative immunohistochemistry? J Clin Pathol 2007;60:690–693.
4. Hofmann M, Stoss O, Gaiser T, et al. Central HER2 IHC and FISH analysis in a trastuzumab (Herceptin) phase II monotherapy study: assessment of test sensitivity and impact of chromosome 17 polysomy. J Clin Pathol 2008;61:89–94.
5. Tuma RS . Inconsistency of HER2 test raises questions. J Natl Cancer Inst 2007;99:1064–1065.
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