Combined analysis of KRAS and PIK3CA mutations, MET and PTEN expression in primary tumors and corresponding metastases in colorectal cancer-Reference-Cited by-同舟云学术

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Combined analysis of KRAS and PIK3CA mutations, MET and PTEN expression in primary tumors and corresponding metastases in colorectal cancer

Published:2012-08-31 Issue:2 Volume:26 Page:302-313
ISSN:0893-3952
Container-title:Modern Pathology
language:en
Short-container-title:Mod Pathol

Author:

Voutsina Alexandra,Tzardi Maria,Kalikaki Aristea,Zafeiriou Zafeiris,Papadimitraki Elsa,Papadakis Michael,Mavroudis Dimitris,Georgoulias Vassilis

Publisher

Springer Science and Business Media LLC

Subject

Pathology and Forensic Medicine

Link

http://www.nature.com/articles/modpathol2012150.pdf

Reference69 articles.

1. Ross JS, Torres-Mora J, Wagle N et al Biomarker-based prediction of response to therapy for colorectal cancer: current perspective. Am J Clin Pathol 2010;134:478–490.

2. Segal NH, Saltz LB . Evolving treatment of advanced colon cancer. Annu Rev Med 2009;60:207–219.

3. De Roock W, De Vriendt V, Normanno N et al KRAS, BRAF, PIK3CA and PTEN mutations: implications for targeted therapies in metastatic colorectal cancer. Lancet Oncol 2011;12:594–603.

4. Prenen H, De Schutter J, Jacobs B et al PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer. Clin Cancer Res 2009;15:3184–3188.

5. Sartore-Bianchi A, Martini M, Molinari F et al PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies. Cancer Res 2009;69:1851–1857.

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