Tumor-specific downregulation and methylation of the CDH13 (H-cadherin) and CDH1 (E-cadherin) genes correlate with aggressiveness of human pituitary adenomas

Author:

Qian Zhi Rong,Sano Toshiaki,Yoshimoto Katsuhiko,Asa Sylvia L,Yamada Shozo,Mizusawa Noriko,Kudo Eiji

Publisher

Springer Science and Business Media LLC

Subject

Pathology and Forensic Medicine

Reference39 articles.

1. Asa SL, Ezzat S . The pathogenesis of pituitary tumors. Nat Rev Cancer 2002;2:836–849.

2. Lee SW . H-cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancer. Nat Med 1996;2:776–782.

3. Sato M, Mori Y, Sakurada A, et al. H-cadherin (CDH13) gene is inactivated in human lung cancer. Hum Genet 1998;103:96–101.

4. Toyooka KO, Toyooka S, Virmani AK, et al. Loss of expression and aberrant methylation of the CDH13 (H-cadherin) gene in breast and lung carcinomas. Cancer Res 2001;61:4556–4560.

5. Kawakami M, Staub J, Cliby W, et al. Involvement of H-cadherin (CDH13) on 16q in the region of frequent deletion in ovarian cancer. Int J Oncol 1999;15:715–720.

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