Loss of H3K27 tri-methylation is a diagnostic marker for malignant peripheral nerve sheath tumors and an indicator for an inferior survival

Author:

Cleven Arjen H G,Sannaa Ghadah A Al,Briaire-de Bruijn Inge,Ingram Davis R,van de Rijn Matt,Rubin Brian P,de Vries Maurits W,Watson Kelsey L,Torres Kelia E,Wang Wei-Lien,van Duinen Sjoerd G,Hogendoorn Pancras C W,Lazar Alexander J,Bovée Judith V M G

Publisher

Springer Science and Business Media LLC

Subject

Pathology and Forensic Medicine

Reference23 articles.

1. Fletcher CDM, Bridge JA, Hogendoorn PCW et al. Malignant peripheral nerve sheath tumour. Hogendoorn PCW, Mertens F (eds). WHO Classification of Tumours of Soft Tissue and Bone. International Agency for Research on Cancer (IARC): France, 2013, p187.

2. Goldblum JR, Folpe AL, Weiss SW . Malignant peripheral nerve sheath tumors. Goldblum JR, Folpe AL, Weiss SW (eds). Soft Tissue Tumors. 6th edn. Elsevier Saunders: USA, 2014;p 867.

3. Kroep JR, Ouali M, Gelderblom H et al. First-line chemotherapy for malignant peripheral nerve sheath tumor (MPNST) versus other histological soft tissue sarcoma subtypes and as a prognostic factor for MPNST: an EORTC soft tissue and bone sarcoma group study. Ann Oncol 2011;22:207–214.

4. Nonaka D, Chiriboga L, Rubin BP . Differential expression of S100 protein subtypes in malignant melanoma, and benign and malignant peripheral nerve sheath tumors. J Cutan Pathol 2008;35:1014–1019.

5. Hirose T, Hasegawa T, Kudo E et al. Malignant peripheral nerve sheath tumors: an immunohistochemical study in relation to ultrastructural features. Hum Pathol 1992;23:865–870.

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