In vitro glucocorticoid resistance in childhood leukemia correlates with receptor affinity determined at 37°C, but not with affinity determined at room temperature

Author:

Haarman EG,Kaspers GJL,Pieters R,Rottier MMA,Den Boer ML,Janka-Schaub GE,Veerman AJP

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Reference8 articles.

1. Kaspers GJL, Pieters R, Van Zantwijk CH, Van Wering ER, Van der Does-van den Berg A, Veerman AJP . Prednisolone resistance in childhood acute lymphoblastic leukemia: vitro–vivo correlations and cross-resistance to other drugs Blood 1998 92: 259–266

2. Moalli PA, Rosen ST . Glucocorticoid receptors and resistance to glucocorticoids in hematologic malignancies Leuk Lymphoma 1994 15: 363–374

3. Pui CH, Ochs J, Kalwinsky DK, Costlow ME . Impact of treatment efficacy on the prognostic value of glucocorticoid receptor levels in childhood acute lymphoblastic leukemia Leuk Res 1984 8: 345–350

4. Ho GA, Odenwald E, Reiter A, Sauter S, Riehm H . Lack of correlation between glucocorticoid receptor levels, response to prednisone monotherapy and relapse-free survival in childhood leukemia Proc Am Soc Clin Oncol 1991 10: 238 (Abstr.)

5. Quddus FF, Leventhal BG, Boyett JM, Pullen DJ, Crist WM, Borowitz MJ . Glucocorticoid receptors in immunological subtypes of childhood acute lymphocytic leukemia cells: a Pediatric Oncology Group Study Cancer Res 1985 45: 6482–6486

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