Prospective multicentric molecular study for poor prognosis fusion transcripts at diagnosis in adult B-lineage ALL patients: the LALA 94 experience

Author:

Picard C,Hayette S,Bilhou-Nabera C,Cayuela J M,Delabesse E,Frenoy N,Preudhomme C,Dupont M,Bastard C,Bories D,Vaerman J L,Davi F,Dastugue N,Raynaud S,Lafage M,Deschaseaux F,Fest T,Gaub M P,Lhéritier V,Thomas X,Charrin C,Boucheix C,Dombret H,MacIntyre E,Fière D,Gabert J

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Reference9 articles.

1. Dombret H, Gabert J, Boiron JM, Rigal-Huguet F, Blaise D, Thomas X, et al. Groupe d'Etude et de Traitement de la Leucemie Aigue Lymphoblastique de l'Adulte (GET-LALA Group). Outcome of treatment in adults with Philadelphia chromosome-positive acute lymphoblastic leukaemia – results of the prospective multicenter LALA-94 trial. Blood 2002; 100: 2357–2366.

2. Thomas X, Boiron JM, Huguet F, Dombret H, Bradstock K, Vey N et al. Outcome of treatment in adults with acute lymphoblastic leukemia: analysis of the LALA-94 trial. J Clin Oncol 2004; 22: 4075–4086.

3. Kawasaki ES, Clark SS, Coyne MY, Smith SD, Champlin R, Witte ON et al. Diagnosis of chronic myeloid and acute lymphocytic leukemias by detection of leukemia-specific mRNA sequences amplified in vitro. Proc Natl Acad Sci USA 1988; 85: 5698–5702.

4. van Dongen JJ, Macintyre EA, Gabert JA, Delabesse E, Rossi V, Saglio G et al. Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: investigation of minimal residual disease in acute leukemia. Leukemia 1999; 13: 1901–1928.

5. Gleissner B, Gokbuget N, Bartram CR, Janssen B, Rieder H, Janssen JW, et al. German Multicenter Trials of Adult Acute Lymphoblastic Leukemia Study Group. Leading prognostic relevance of the BCR-ABL translocation in adult acute B-lineage lymphoblastic leukemia: a prospective study of the German Multicenter Trial Group and confirmed polymerase chain reaction analysis. Blood 2002; 99: 1536–1543.

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