The histone deacetylase inhibitor ITF2357 selectively targets cells bearing mutated JAK2V617F-Reference-Cited by-同舟云学术

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The histone deacetylase inhibitor ITF2357 selectively targets cells bearing mutated JAK2V617F

Published:2007-12-13 Issue:4 Volume:22 Page:740-747
ISSN:0887-6924
Container-title:Leukemia
language:en
Short-container-title:Leukemia

Author:

Guerini V,Barbui V,Spinelli O,Salvi A,Dellacasa C,Carobbio A,Introna M,Barbui T,Golay J,Rambaldi A

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Link

http://www.nature.com/articles/2405049.pdf

Reference49 articles.

1. Tefferi A, Barbui T . bcr/abl-negative, classic myeloproliferative disorders: diagnosis and treatment. Mayo Clin Proc 2005; 80: 1220–1232.

2. Baxter EJ, Scott LM, Campbell PJ, East C, Fourouclas N, Awanton S et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 2005; 365: 1054–1061.

3. James C, Ugo V, Le Couedic JP, Le Couedic JP, Staerk J, Delhommeau F et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005; 434: 1144–1148.

4. Levine RL, Wadleigh M, Cools J, Ebert BL, Wernig G, Huntly BJ et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 2005; 7: 387–397.

5. Kralovics R, Passamonti F, Buser AS, Teo SS, Tiedt R, Passweg JR et al. A gain-of-function mutation of JAK2 in myeloproliferative disorders. N Engl J Med 2005; 352: 1779–1790.

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