UGT1A1 promoter polymorphism increases risk of nilotinib-induced hyperbilirubinemia-Reference-Cited by-同舟云学术

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UGT1A1 promoter polymorphism increases risk of nilotinib-induced hyperbilirubinemia

Published:2007-07-05 Issue:11 Volume:21 Page:2311-2315
ISSN:0887-6924
Container-title:Leukemia
language:en
Short-container-title:Leukemia

Author:

Singer J B,Shou Y,Giles F,Kantarjian H M,Hsu Y,Robeva A S,Rae P,Weitzman A,Meyer J M,Dugan M,Ottmann O G

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Link

http://www.nature.com/articles/2404827.pdf

Reference19 articles.

1. Bosma PJ, Seppen J, Goldhoorn B, Bakker C, Oude Elferink RP, Chowdhury JR et al. Bilirubin UDP-glucuronosyltransferase 1 is the only relevant bilirubin glucuronidating isoform in man. J Biol Chem 1994; 269: 17960–17964.

2. Bosma PJ, Chowdhury JR, Bakker C, Gantla S, de Boer A, Oostra BA et al. The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome. N Engl J Med 1995; 333: 1171–1175.

3. Monaghan G, Ryan M, Seddon R, Hume R, Burchell B . Genetic variation in bilirubin UPD-glucuronosyltransferase gene promoter and Gilbert's syndrome. Lancet 1996; 347: 578–581.

4. Beutler E, Gelbart T, Demina A . Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism? Proc Natl Acad Sci USA 1998; 95: 8170–8174.

5. Premawardhena A, Fisher CA, Liu YT, Verma IC, de Silva S, Arambepola M et al. The global distribution of length polymorphisms of the promoters of the glucuronosyltransferase 1 gene (UGT1A1): hematologic and evolutionary implications. Blood Cells Mol Dis 2003; 31: 98–101.

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