Treatment of childhood acute myeloblastic leukemia: dose intensification improves outcome and maintenance therapy is of no benefit – multicenter studies of the French LAME (Leucémie Aiguë Myéloblastique Enfant) Cooperative Group

Author:

Perel Y, ,Auvrignon A,Leblanc T,Michel G,Reguerre Y,Vannier J-P,Dalle J-H,Gandemer V,Schmitt C,Méchinaud F,Lejars O,Piguet C,Couillaud G,Pautard B,Landman-Parker J,Thuret I,Aladjidi N,Baruchel A,Leverger G

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Reference29 articles.

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2. Michel G, Leverger G, Leblanc T, Nelken B, Baruchel A, Landman-Parker J et al. Allogeneic bone marrow transplantation vs aggressive post-remission chemotherapy for children with acute myeloid leukemia in first complete remission. A prospective study from the French Society of Pediatric Hematology and Immunology (SHIP). Bone Marrow Transplant 1996; 17: 191–196.

3. Perel Y, Auvrignon A, Leblanc T, Vannier JP, Michel G, Nelken B et al. Impact of addition of maintenance therapy to intensive induction and consolidation chemotherapy for childhood acute myeloblastic leukemia: results of a prospective randomized trial, LAME 89/91. J Clin Oncol 2002; 20: 2774–2782.

4. Lie SO, Jonmundsson G, Mellander L, Siimes MA, Yssing M, Gustafsson G . A population-based study of 272 children with acute myeloid leukaemia treated on two consecutive protocols with different intensity: best outcome in girls, infants, and children with Down's syndrome. Nordic Society of Paediatric Haematology and Oncology (NOPHO). Br J Haematol 1996; 94: 82–88.

5. Lie SO, Abrahamsson J, Clausen N, Forestier E, Hasle H, Hovi L et al. Treatment stratification based on initial in vivo response in acute myeloid leukaemia in children without Down's syndrome: results of NOPHO-AML trials. Br J Haematol 2003; 122: 217–225.

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