Amifostine (WR-2721) selective protection against melphalan genotoxicity

Author:

Buschini A,Anceschi E,Carlo-Stella C,Regazzi E,Rizzoli V,Poli P,Rossi C

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Reference68 articles.

1. Glover DJ, Fox KR, Weiler C, Kligerman MM, Turrisi A, Glick JH . Clinical trials of WR-2721 prior to alkylating agent chemotherapy and radiotherapy Pharmacol Ther 1988 39: 3–7

2. Smoluk GD, Fahey RC, Calabro-Jones PM, Aguilera JA, Ward JF . Radioprotection of cells in culture by WR-2721 and derivatives: form of the drug responsible for protection Cancer Res 1988 48: 3641–3647

3. Littlefield LG, Joiner EE, Colyer SP, Frome EL . Concentration dependent protection against X-ray induced chromosome aberrations in human lymphocytes by the aminothiol WR-1065 Radiat Res 1993 133: 88–94

4. Clark LS, Albertini RJ, Nicklas JA . The aminothiol WR-1065 protects T lymphocytes from ionizing radiation-induced deletions of the HPRT gene Cancer Epidemiol Biomarkers Prev 1997 6: 1033–1037

5. Wasserman TH, Phillips TL, Ross G, Kane LJ . Differential protection against cytotoxic chemotherapeutic effects on bone marrow CFUs by WR-2721 Cancer Clin Trials 1981 4: 3–6

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