Effect of methotrexate polyglutamates on thioguanine nucleotide concentrations during continuation therapy of acute lymphoblastic leukemia with mercaptopurine
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Cancer Research,Hematology
Link
http://www.nature.com/articles/2402373.pdf
Reference21 articles.
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2. McLeod H, Krynetski E, Relling MV, Evans WE . Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia Leukemia 2000 14: 567–572
3. Lennard L, Lilleyman JS, Van Loon J, Weinshilboum RM . Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia Lancet 1990 336: 225–229
4. Relling MV, Hancock ML, Rivera GK, Sandlund JT, Ribeiro RC, Krynetski EY, Pui C-H, Evans WE . Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus J Natl Cancer Inst 1999 91: 2001–2008
5. Giverhaug T, Loennechen T, Aarbakke J . The interaction of 6-mercaptopurine (6-MP) and methotrexate (MTX) Gen Pharmacol 1999 33: 341–346
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