Quantitative assessment of WT1 expression by real time quantitative PCR may be a useful tool for monitoring minimal residual disease in acute leukemia patients

Author:

Cilloni D,Gottardi E,De Micheli D,Serra A,Volpe G,Messa F,Rege-Cambrin G,Guerrasio A,Divona M,Lo Coco F,Saglio G

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Reference23 articles.

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2. Cave H, van der Werfften Bosch J, Suciu S, Guidal C, Waterkeeyn C, Otten J, Bakkus M, Thielemans K, Grandchamp B, Vilmer E . Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia. European Organization for Research and Treatment of Cancer-Childhood Leukemia Cooperative Group N Engl J Med 1998 27: 591–598

3. Lo Coco F, Diverio D, Falini B, Biondi A, Nervi C, Pelicci PG . Genetic diagnosis and molecular monitoring in the management of acute promyelocytic leukemia Blood 1999 94: 12–22

4. Diverio D, Rossi V, Avvisati G, De Santis S, Pistilli A, Pane F, Saglio G, Martinelli G, Petti MG, Santoro A, Pelicci PG, Mandelli F, Biondi A, Lo Coco F . Early detection of relapse by prospective reverse transcriptase-polymerase chain reaction analysis of the PML/RARα fusion gene in patients with acute promyelocytic leukemia enrolled in the GIMEMA-AIEOP multicenter ‘AIDA’ trial. GIMEMA-AIEOP Multicenter ‘AIDA’ Trial Blood 1998 92: 784–789

5. Call KM, Glaser T, Ito CY, Bukler AJ, Pelletier J, Haber DA, Rose EA, Kral A, Yeger H, Lewis WH . Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms’ tumor locus Cell 1990 60: 509–520

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