Elevated mRNA transcripts of non-homologous end-joining genes in pediatric acute lymphoblastic leukemia

Author:

Chiou S-S,Huang J-L,Tsai Y-S,Chen T-F,Lee K-W,Juo S-H H,Jong Y-J,Hung C-H,Chang T-T,Lin C-S

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Reference9 articles.

1. Khanna KK, Jackson SP . DNA double-strand breaks: signaling, repair and the cancer connection. Nat Genet 2001; 27: 247–254.

2. Brady N, Gaymes TJ, Cheung M, Mufti GJ, Rassool FV . Increased error-prone NHEJ activity in myeloid leukemias is associated with DNA damage at sites that recruit key nonhomologous end-joining proteins. Cancer Res 2003; 63: 1798–1805.

3. Gaymes TJ, Mufti GJ, Rassool FV . Myeloid leukemias have increased activity of the nonhomologous end-joining pathway and concomitant DNA misrepair that is dependent on the Ku70/86 heterodimer. Cancer Res 2002; 62: 2791–2797.

4. Rassool FV . DNA double strand breaks (DSB) and non-homologous end joining (NHEJ) pathways in human leukemia. Cancer Lett 2003; 193: 1–9.

5. Greaves MF, Wiemels J . Origins of chromosome translocations in childhood leukaemia. Nat Rev Cancer 2003; 3: 639–649.

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