Major form of NUP98/HOXC11 fusion in adult AML with t(11;12)(p15;q13) translocation exhibits aberrant trans-regulatory activity-Reference-Cited by-同舟云学术

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Major form of NUP98/HOXC11 fusion in adult AML with t(11;12)(p15;q13) translocation exhibits aberrant trans-regulatory activity

Published:2003-09 Issue:9 Volume:17 Page:1858-1864
ISSN:0887-6924
Container-title:Leukemia
language:en
Short-container-title:Leukemia

Author:

Gu B-W,Wang Q,Wang J-M,Xue Y-Q,Fang J,Wong K F,Chen B,Shi Z-Z,Shi J-Y,Bai X-T,Wu D-H,Chen Z,Chen S-J

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Link

http://www.nature.com/articles/2403036.pdf

Reference37 articles.

1. Radu A, Moore MS, Blobel G . The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex. Cell 1995; 81: 215–222.

2. Powers MA, Forbes DJ, Dahlberg JE, Lund E . The vertebrate GLFG nucleoporin, Nup98, is an essential component of multiple RNA export pathways. J Cell Biol 1997; 136: 241–250.

3. Lam DH, Aplan PD . NUP98 gene fusions in hematologic malignancies. Leukemia 2001; 15: 1689–1695.

4. Nakamura T, Largaespada DA, Lee MP, Johnson LA, Ohyashiki K, Toyama K et al. Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia. Nat Genet 1996; 12: 154–158.

5. Arai Y, Hosoda F, Kobayashi H, Arai K, Hayashi Y, Kamada N et al. The inv(11)(p15q22) chromosome translocation of de novo and therapy-related myeloid malignancies results in fusion of the nucleoporin gene, NUP98, with the putative RNA helicase gene, DDX10. Blood 1997; 89: 3936–3944.

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1. NUP98 Rearrangements in AML: Molecular Mechanisms and Clinical Implications;Onco;2023-07-18

2. HOXC11 drives lung adenocarcinoma progression through transcriptional regulation of SPHK1;Cell Death & Disease;2023-02-23

3. Inherited heterozygous Fanconi anemia gene mutations in a therapy-related CMML patient with a rare NUP98-HOXC11 fusion: A case report;Frontiers in Oncology;2022-10-19

4. HOXC11 positively regulates the long non-coding RNA HOTAIR and is associated with poor prognosis in colon adenocarcinoma;Experimental and Therapeutic Medicine;2021-09-16

5. HOXC11 Expression Is Associated with the Progression of Colon Adenocarcinoma and Is a Prognostic Biomarker;DNA and Cell Biology;2021-09-01

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