The histone deacetylase inhibitor valproic acid potently augments gemtuzumab ozogamicin-induced apoptosis in acute myeloid leukemic cells
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Cancer Research,Hematology
Link
http://www.nature.com/articles/2404477.pdf
Reference21 articles.
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2. Dinndorf PA, Andrews RG, Benjamin D, Ridgway D, Wolff L, Bernstein ID . Expression of normal myeloid-associated antigens by acute leukemia cells. Blood 1986; 67: 1048–1053.
3. Amico D, Barbui AM, Erba E, Rambaldi A, Introna M, Golay J . Differential response of human acute myeloid leukemia cells to gemtuzumab ozogamicin in vitro: role of Chk1 and Chk2 phosphorylation and caspase 3. Blood 2003; 101: 4589–4597.
4. Schwemmlein M, Peipp M, Barbin K, Saul D, Stockmeyer B, Repp R et al. A CD33-specific single-chain immunotoxin mediates potent apoptosis of cultured human myeloid leukaemia cells. Br J Haematol 2006; 133: 141–151.
5. Sperr WR, Florian S, Hauswirth AW, Valent P . CD 33 as a target of therapy in acute myeloid leukemia: current status and future perspectives. Leuk Lymphoma 2005; 46: 1115–1120.
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