NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component-Reference-Cited by-同舟云学术

NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component

Published:2015-12-07 Issue:3 Volume:17 Page:250-258
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Shi Hexin,Wang Ying,Li Xiaohong,Zhan Xiaoming,Tang Miao,Fina Maggy,Su Lijing,Pratt David,Bu Chun Hui,Hildebrand Sara,Lyon Stephen,Scott Lindsay,Quan Jiexia,Sun Qihua,Russell Jamie,Arnett Stephanie,Jurek Peter,Chen Ding,Kravchenko Vladimir V,Mathison John C,Moresco Eva Marie Y,Monson Nancy L,Ulevitch Richard J,Beutler Bruce

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/ni.3333.pdf

Reference36 articles.

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2. Zhou, R., Yazdi, A.S., Menu, P. & Tschopp, J. A role for mitochondria in NLRP3 inflammasome activation. Nature 469, 221–225 (2011).

3. Subramanian, N., Natarajan, K., Clatworthy, M.R., Wang, Z. & Germain, R.N. The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation. Cell 153, 348–361 (2013).

4. Misawa, T. et al. Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome. Nat. Immunol. 14, 454–460 (2013).

5. Roig, J., Mikhailov, A., Belham, C. & Avruch, J. Nercc1, a mammalian NIMA-family kinase, binds the Ran GTPase and regulates mitotic progression. Genes Dev. 16, 1640–1658 (2002).

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