Allosteric coupling between proximal C-terminus and selectivity filter is facilitated by the movement of transmembrane segment 4 in TREK-2 channel
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep21248.pdf
Reference45 articles.
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3. Pereira, V. et al. Role of the TREK2 potassium channel in cold and warm thermosensation and in pain perception. Pain 155, 2534–2544 (2014).
4. Xiao, Z. et al. Activation of neurotensin receptor 1 facilitates neuronal excitability and spatial learning and memory in the entorhinal cortex: beneficial actions in an Alzheimer’s disease model. J Neurosci 34, 7027–7042 (2014).
5. Xiao, Z. et al. Noradrenergic depression of neuronal excitability in the entorhinal cortex via activation of TREK-2 K+ channels. J Biol Chem 284, 10980–10991 (2009).
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