Uptake of apoptotic cells drives the growth of a pathogenic trypanosome in macrophages

Author:

Freire-de-Lima Célio G.,Nascimento Danielle O.,Soares Milena B. P.,Bozza Patricia T.,Castro-Faria-Neto Hugo C.,de Mello Fernando G.,DosReis George A.,Lopes Marcela F.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference29 articles.

1. Savill, J. Apoptosis: Phagocytic docking without shocking. Nature 392, 442–443 (1998).

2. Voll, R. E., Herrmann, M., Roth, E. A., Stach, C. & Kalden, J. R. Immunosuppressive effects of apoptotic cells. Nature 390, 350–351 (1997).

3. Fadok, V. A. et al. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-β, PGE2 and PAF. J. Clin. Invest. 101, 890–898 (1998).

4. Lopes, M. F., Veiga, V. F., Santos, A. R., Fonseca, M. E. F. & DosReis, G. A. Activation-induced CD4+ T cell death by apoptosis in experimental Chagas disease. J. Immunol. 154, 744–752 (1995).

5. Nunes, M. P., Andrade, R. M., Lopes, M. F. & DosReis, G. A. Activation-induced T cell death exacerbates Trypanosoma cruzi replication in macrophages cocultured with CD4+ T lymphocytes from infected hosts. J. Immunol. 160, 1313–1319 (1998).

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