The chemokine CXCL14 is negatively associated with obesity and concomitant type-2 diabetes in humans
Author:
Publisher
Springer Science and Business Media LLC
Subject
Nutrition and Dietetics,Endocrinology, Diabetes and Metabolism,Medicine (miscellaneous)
Link
http://www.nature.com/articles/s41366-020-00732-y.pdf
Reference12 articles.
1. Lu J, Chatterjee M, Schmid H, Beck S, Gawaz M. CXCL14 as an emerging immune and inflammatory modulator. J Inflamm. 2016;13:1. https://doi.org/10.1186/s12950-015-0109-9.
2. Cereijo R, Gavaldà-Navarro A, Cairó M, Quesada-López T, Villarroya J, Morón-Ros S, et al. CXCL14, a brown adipokine that mediates brown-fat-to-macrophage communication in thermogenic adaptation. Cell Metab. 2018;28:750–63. https://doi.org/10.1016/j.cmet.2018.07.015.
3. Nara N, Nakayama Y, Okamoto S, Tamura H, Kiyono M, Muraoka M, et al. Disruption of CXC motif chemokine ligand-14 in mice ameliorates obesity-induced insulin resistance. J Biol Chem. 2007;282:30794–803. https://doi.org/10.1074/jbc.M700412200.
4. Takahashi M, Takahashi Y, Takahashi K, Zolotaryov FN, Hong KS, Iida K, et al. CXCL14 enhances insulin-dependent glucose uptake in adipocytes and is related to high-fat diet-induced obesity. Biochem Biophys Res Commun. 2007;364:1037–42. https://doi.org/10.1016/j.bbrc.2007.10.120.
5. Atanes P, Hawkes RG, Olaniru OE, Ruz-Maldonado I, Amisten S, Persaud SJ. CXCL14 Inhibits Insulin Secretion Independently of CXCR4 or CXCR7 Receptor Activation or cAMP Inhibition. Cell Physiol Biochem. 2014;52:879–92. https://doi.org/10.33594/000000061.
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