Reinforcing Effects Of Compounds Lacking Intrinsic Efficacy At α1 Subunit-Containing GABAA Receptor Subtypes in Midazolam- But Not Cocaine-Experienced Rhesus Monkeys-Reference-Cited by-同舟云学术

Reinforcing Effects Of Compounds Lacking Intrinsic Efficacy At α1 Subunit-Containing GABAA Receptor Subtypes in Midazolam- But Not Cocaine-Experienced Rhesus Monkeys

Published:2012-12-27 Issue:6 Volume:38 Page:1006-1014
ISSN:0893-133X
Container-title:Neuropsychopharmacology
language:en
Short-container-title:Neuropsychopharmacol

Author:

Shinday Nina M,Sawyer Eileen K,Fischer Bradford D,Platt Donna M,Licata Stephanie C,Atack John R,Dawson Gerard R,Reynolds David S,Rowlett James K

Publisher

Springer Science and Business Media LLC

Subject

Psychiatry and Mental health,Pharmacology

Link

http://www.nature.com/articles/npp2012265.pdf

Reference35 articles.

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3. Atack JR, Wafford KA, Tye SJ, Cook SM, Sohal B, Pike A et al (2006). TPA023 (7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo(4,3-b)pyridazine), an agonist selective for alpha2- and alpha3-containing GABAA receptors, is a nonsedating anxiolytic in rodents and primates. J Pharmacol Exp Ther 316: 410–422.

4. Ator NA (2002). Relation between discriminative and reinforcing effects of midazolam, pentobarbital, chlordiazepoxide, zolpidem, and imidazenil in baboons. Psychopharmacology (Berl) 163: 477–487.

5. Ator NA, Atack JR, Hargreaves RJ, Burns HD, Dawson GR (2010). Reducing abuse liability of GABAA/benzodiazepine ligands via selective partial agonist efficacy at alpha1 and alpha2/3 subtypes. J Pharmacol Exp Ther 332: 4–16.

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