Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson’s disease
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cellular and Molecular Neuroscience,Clinical Neurology,Neurology
Link
http://www.nature.com/articles/s41531-017-0032-2.pdf
Reference74 articles.
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3. Goldman, S. M. Environmental toxins and Parkinson’s disease. Annu. Rev. Pharmacol. Toxicol. 54, 141–164 (2014).
4. Mullin, S. & Schapira, A. H. Pathogenic mechanisms of neurodegeneration in Parkinson disease. Neurol. Clin. 33, 1–17 (2015).
5. Block, M. L., Zecca, L. & Hong, J. S. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat. Rev. Neurosci. 8, 57–69 (2007).
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