C6-ceramide nanoliposome suppresses tumor metastasis by eliciting PI3K and PKCζ tumor-suppressive activities and regulating integrin affinity modulation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep09275.pdf
Reference58 articles.
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2. Stover, T. & Kester, M. Liposomal delivery enhances short-chain ceramide-induced apoptosis of breast cancer cells. J Pharmacol Exp Ther 307, 468–475, 10.1124/jpet.103.054056 (2003).
3. Fox, T. E. et al. Ceramide recruits and activates protein kinase C zeta (PKC zeta) within structured membrane microdomains. J Biol Chem 282, 12450–12457, 10.1074/jbc.M700082200 (2007).
4. Tagaram, H. R. et al. Nanoliposomal ceramide prevents in vivo growth of hepatocellular carcinoma. Gut 60, 695–701, 10.1136/gut.2010.216671 (2011).
5. Ryland, L. K. et al. C6-ceramide nanoliposomes target the Warburg effect in chronic lymphocytic leukemia. PLoS One 8, e84648, 10.1371/journal.pone.0084648 (2013).
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