Mutant p53 partners in crime
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/cdd2017185.pdf
Reference40 articles.
1. Liu Y, Chen C, Xu Z, Scuoppo C, Rillahan CD, Gao J et al. Deletions linked to TP53 loss drive cancer through p53-independent mechanisms. Nature 2016; 531: 471–475.
2. Milner J, Medcalf EA, Cook AC . Tumor suppressor p53: analysis of wild-type and mutant p53 complexes. Mol Cell Biol 1991; 11: 12–19.
3. Willis A, Jung EJ, Wakefield T, Chen X . Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes. Oncogene 2004; 23: 2330–2338.
4. Lang GA, Iwakuma T, Suh YA, Liu G, Rao VA, Parant JM et al. Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome. Cell 2004; 119: 861–872.
5. Milner J, Medcalf EA . Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation. Cell 1991; 65: 765–774.
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