The ubiquitin ligase LIN41/TRIM71 targets p53 to antagonize cell death and differentiation pathways during stem cell differentiation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/cdd201754.pdf
Reference52 articles.
1. Strikoudis A, Guillamot M, Aifantis I . Regulation of stem cell function by protein ubiquitylation. EMBO Rep 2014; 15: 365–382.
2. Slack FJ, Basson M, Liu Z, Ambros V, Horvitz HR, Ruvkun G . The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol Cell 2000; 5: 659–669.
3. Ecsedi M, Rausch M, Grosshans H . The let-7 microRNA directs vulval development through a single target. Dev Cell 2015; 32: 335–344.
4. Worringer KA, Rand TA, Hayashi Y, Sami S, Takahashi K, Tanabe K et al. The let-7/LIN-41 pathway regulates reprogramming to human induced pluripotent stem cells by controlling expression of prodifferentiation genes. Cell Stem Cell 2014; 14: 40–52.
5. Chang H-M, Martinez NJ, Thornton JE, Hagan JP, Nguyen KD, Gregory RI . Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation. Nat Commun 2012; 3: 923.
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