Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice-Reference-Cited by-同舟云学术

Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

Published:1998-09 Issue:1 Volume:20 Page:78-82
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Xu Tianshun,Bianco Paolo,Fisher Larry W.,Longenecker Glenn,Smith Erica,Goldstein Steven,Bonadio Jeffrey,Boskey Adele,Heegaard Anne-Marie,Sommer Beatrice,Satomura Kazuhito,Dominguez Pedro,Zhao Chengyan,Kulkarni Ashok B.,Robey Pamela Gehron,Young Marian F.

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

http://www.nature.com/articles/ng0998_78.pdf

Reference33 articles.

1. Fisher, L.W. et al. Proteoglycans of developing bone. J. Biol. Chem. 258, 6588–6594 (1983).

2. Bianco, P., Fisher, L.W., Young, M.F., Termine, J.D. & Robey, P.G. Expression and localization of the two small proteoglycans biglycan and decorin in developing human skeletal and non-skeletal tissues. J. Histochem. Cytochem. 38, 1549–1563 (1990).

3. Fisher, L.W., Termine, J.D. & Young, M.F. Deduced protein sequence of bone small proteoglycan I (biglycan) shows homology with proteoglycan II (decorin) and several nonconnective tissue proteins in a variety of species. J. Biol. Chem. 264, 4571–4576 (1989).

4. Schönherr, E. et al. Interaction of biglycan with type I collagen. J. Biol. Chem. 270, 2776–2783 (1995).

5. Yamaguchi, Y., Mann, D.M. & Ruoslahti, E. Negative regulation of transforming growth factor-beta by the proteoglycan decorin. Nature 346, 281–284 (1990).

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